Concept of Immunology:-
- The overall
ability of the host fight against the disease causing organisms, provided by
the immune system is called immunity.
- The immune
system of our body consists of lymphoid organs, tissues, cell and soluble
molecules like antibodies.
- The primary
lymphoid organs are bone marrow and thymus. The secondary lymphoid organs like
spleen, lymph nodes, tonsils, peyer's patches of small intestine and appendix.
- The bone
marrow is the main lymphoid organ, where all blood cells including lymphocytes
are produced. The thymus is a lobed organ, located near the heart and beneath
the breast bone.
- Both bone
marrow and thymus provide micro-environments for the development and maturation
of T-lymphocytes. The spleen is a large been shaped organ. It mainly contains
lymphocytes and phagocytes. It also reservoir of erythrocytes.
- The lymph
nodes are located at different points along the lymphatic system. They trap the
microbes or antigens. These antigens are responsible for the activation of lymphocytes
causing the immune response.
- A lymphoid
tissue is also located within the lining of the major tracts called Mucosal
Associated Lymphoid tissue. It constitutes about 50% of the lymphoid tissue in
human body.
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